This oven baked 3-ingredients mayo parmesan chicken is the exact weeknight lifesaver my sister-in-law shared with me when I first went back to work after maternity leave. I was exhausted, hungry, and totally over complicated recipes. She told me, “Trust me, just chicken, mayo, and Parmesan. That’s it.” I was skeptical, but the first time I pulled this golden, bubbly chicken out of the oven, I was hooked. The mayo keeps the chicken incredibly juicy, the Parmesan melts into a salty, cheesy crust, and the whole thing bakes in one glass casserole dish. It’s the kind of no-brainer, minimal-cleanup dinner that fits right into a busy Midwest weeknight—especially when you’re juggling work, kids, and everything else life throws at you.
I usually serve this mayo Parmesan chicken with something equally low-effort: a bagged salad kit, roasted broccoli, or steamed green beans tossed with a little butter and salt. It’s also great over buttered egg noodles or simple white rice to soak up the extra creamy, cheesy drippings from the pan. If you want to round it out a bit more, add a side of garlic bread or dinner rolls and some sliced cucumbers or cherry tomatoes for something fresh and crunchy on the plate.
Oven Baked 3-Ingredient Mayo Parmesan Chicken
Servings: 4
Ingredients
4 boneless skinless chicken breasts (about 2 pounds total)
1 cup mayonnaise
1 cup grated Parmesan cheese (the dry, shaker-can style works great)
Directions
Preheat your oven to 400°F (200°C). Lightly grease a glass 9x13-inch casserole dish or coat it with a quick swipe of mayonnaise so the chicken doesn’t stick.
Pat the chicken breasts dry with paper towels. This helps the mayo-Parmesan mixture cling better and gives you a nicer golden top.
Lay the chicken breasts in a single layer in the prepared glass casserole dish, leaving a little space between each piece so they bake evenly.
In a small bowl, stir together the mayonnaise and grated Parmesan cheese until well combined and creamy.
Spoon the mayo-Parmesan mixture evenly over the tops of the chicken breasts, spreading it all the way to the edges of each piece to fully coat the top. The layer should be fairly thick; this is what keeps the chicken moist and creates that golden, cheesy crust.
Place the casserole dish on the middle rack of the preheated oven and bake for 25–30 minutes, or until the chicken is cooked through (the internal temperature should reach 165°F/74°C and the juices run clear).
Once the chicken is cooked, switch the oven to broil on high and broil for 2–3 minutes, watching closely, just until the tops are deep golden brown and bubbly. This step gives you that picture-perfect, slightly crisp, cheesy crust.
Remove the dish from the oven and let the chicken rest for 5 minutes in the casserole dish before serving. This helps the juices settle and makes it easier to slice or serve whole breasts straight from the pan.
Variations & Tips
To keep the spirit of the 3-ingredient secret, I treat seasonings as optional add-ons, not required ingredients. If you want to tweak it a bit, you can sprinkle the chicken lightly with salt, pepper, garlic powder, or Italian seasoning before spreading on the mayo-Parmesan mixture. For a little extra texture, stir in a couple of tablespoons of plain breadcrumbs with the Parmesan to create a more pronounced crust on top. If your chicken breasts are very large and thick, slice them horizontally into cutlets so they cook faster and more evenly on busy nights. You can also swap half of the mayonnaise for plain Greek yogurt if you like a slightly tangier flavor while still keeping the recipe simple. Leftovers reheat surprisingly well—slice the cold chicken and use it in sandwiches or on top of salads for an easy next-day lunch, which is another small way this 3-ingredient trick keeps helping out on hectic weekdays.